Supplement Catalog

Explore supplements commonly mentioned in longevity protocols. Each entry includes typical dosing, timing, and important interaction warnings.

Expert:Bryan Johnson

Botanicals
Ashwagandha (Withania somnifera) Root Extract
Ashwagandha is an adaptogenic herb traditionally used in Ayurvedic medicine, with modern research suggesting it may help reduce stress, anxiety, and cortisol levels. Clinical studies have primarily used standardized root extracts containing 1.5-35% withanolides, the plant's active compounds. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 1 expert
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Compounds
Calcium Alpha-Ketoglutarate (Ca-AKG)
Calcium Alpha-Ketoglutarate is a calcium salt of alpha-ketoglutaric acid, a naturally occurring compound involved in cellular energy production and metabolism. Research suggests it may support healthy aging by addressing multiple pathways including mitochondrial function and epigenetic processes, though human longevity studies are limited. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 1 expert
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Compounds
CoQ10 (Ubiquinol)
Coenzyme Q10 is a naturally occurring compound that plays a vital role in cellular energy production and acts as a powerful antioxidant. Ubiquinol is the active, reduced form of CoQ10 that is better absorbed than conventional CoQ10 supplements. It supports heart health, may help reduce migraine frequency, and can help counteract the natural decline in CoQ10 levels that occurs with aging.
Recommended by 4 experts
Learn more
Compounds
Fisetin
Fisetin is a natural flavonoid compound found in strawberries and other fruits that has gained attention for its potential senolytic properties - the ability to help clear damaged 'senescent' cells from the body. Research suggests it may support cellular health and cognitive function, though human studies are still limited. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more
Minerals
Magnesium
Magnesium is an essential mineral involved in over 300 enzymatic reactions in the body, supporting muscle function, nerve transmission, blood sugar regulation, and bone health. Common forms include magnesium glycinate, oxide, and citrate, with varying absorption rates and specific benefits. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 5 experts
Learn more
Amino Acids
NAC (N-Acetylcysteine)
NAC is a derivative of the amino acid cysteine that serves as a precursor to glutathione, the body's most powerful antioxidant. It's commonly used to support liver detoxification, respiratory health, and cellular protection against oxidative stress. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more
Compounds
Nicotinamide Riboside (NR)
Nicotinamide riboside (NR) is a form of vitamin B3 that serves as a precursor to NAD+ (nicotinamide adenine dinucleotide), an essential molecule found in every living cell that supports cellular energy production and metabolism. Clinical studies show NR supplementation can effectively increase blood NAD+ levels, though benefits may be most apparent in clinical populations with specific health conditions rather than healthy individuals. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more
Compounds
NMN (Nicotinamide Mononucleotide)
NMN is a naturally occurring compound that serves as a precursor to NAD+, a crucial molecule for cellular energy production and DNA repair. Research suggests it may support healthy aging by improving muscle function, insulin sensitivity, and cardiovascular health. While promising, human clinical trials are still limited and more research is needed to confirm long-term benefits.
Recommended by 3 experts
Learn more
Fatty Acids
Omega-3 Fish Oil (EPA/DHA)
Omega-3 fish oil supplements provide essential fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) that support cardiovascular health, reduce inflammation, and may benefit cognitive function. These supplements are derived from fatty fish and provide concentrated amounts of omega-3s that may be difficult to obtain from diet alone. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 6 experts
Learn more
Compounds
Resveratrol
Resveratrol is a polyphenolic compound naturally found in red wine, grapes, and berries that acts as a powerful antioxidant in the body. Research suggests it may support cardiovascular health, cognitive function, and healthy aging through its anti-inflammatory properties. Clinical studies have shown potential benefits for blood sugar control, weight management, and brain health, though more long-term research is needed.
Recommended by 2 experts
Learn more
Compounds
Spermidine
Spermidine is a naturally occurring polyamine compound that plays a crucial role in cellular autophagy, the body's process of cleaning out damaged cells and regenerating healthier ones. As spermidine levels decline with age, supplementation may support longevity and cognitive function, though long-term human studies are still limited. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more
Vitamins
Vitamin B12 (Cyanocobalamin/Methylcobalamin)
Vitamin B12 is an essential water-soluble vitamin that maintains healthy nerve cells, supports red blood cell formation, and aids in DNA synthesis. It plays a crucial role in brain function, energy metabolism, and preventing megaloblastic anemia. This vitamin is particularly important for neurological health and cognitive function as we age.
Recommended by 5 experts
Learn more
Vitamins
Vitamin D3 (Cholecalciferol)
Vitamin D3 is the active form of vitamin D that supports bone health, immune function, and cardiovascular health by helping the body absorb calcium and phosphorus. Adults over 50 often have reduced vitamin D synthesis and may benefit from supplementation to maintain optimal blood levels. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 6 experts
Learn more
Minerals
Zinc
Zinc is an essential mineral that plays crucial roles in immune function, wound healing, protein synthesis, and DNA formation. It supports over 300 enzymatic reactions in the body and may help reduce the duration of common cold symptoms when taken early. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more

Botanicals
Ashwagandha (Withania somnifera) Root Extract
Ashwagandha is an adaptogenic herb traditionally used in Ayurvedic medicine, with modern research suggesting it may help reduce stress, anxiety, and cortisol levels. Clinical studies have primarily used standardized root extracts containing 1.5-35% withanolides, the plant's active compounds. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 1 expert
Learn more
Compounds
Calcium Alpha-Ketoglutarate (Ca-AKG)
Calcium Alpha-Ketoglutarate is a calcium salt of alpha-ketoglutaric acid, a naturally occurring compound involved in cellular energy production and metabolism. Research suggests it may support healthy aging by addressing multiple pathways including mitochondrial function and epigenetic processes, though human longevity studies are limited. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 1 expert
Learn more
Compounds
CoQ10 (Ubiquinol)
Coenzyme Q10 is a naturally occurring compound that plays a vital role in cellular energy production and acts as a powerful antioxidant. Ubiquinol is the active, reduced form of CoQ10 that is better absorbed than conventional CoQ10 supplements. It supports heart health, may help reduce migraine frequency, and can help counteract the natural decline in CoQ10 levels that occurs with aging.
Recommended by 4 experts
Learn more
Compounds
Fisetin
Fisetin is a natural flavonoid compound found in strawberries and other fruits that has gained attention for its potential senolytic properties - the ability to help clear damaged 'senescent' cells from the body. Research suggests it may support cellular health and cognitive function, though human studies are still limited. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more
Minerals
Magnesium
Magnesium is an essential mineral involved in over 300 enzymatic reactions in the body, supporting muscle function, nerve transmission, blood sugar regulation, and bone health. Common forms include magnesium glycinate, oxide, and citrate, with varying absorption rates and specific benefits. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 5 experts
Learn more
Amino Acids
NAC (N-Acetylcysteine)
NAC is a derivative of the amino acid cysteine that serves as a precursor to glutathione, the body's most powerful antioxidant. It's commonly used to support liver detoxification, respiratory health, and cellular protection against oxidative stress. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more
Compounds
Nicotinamide Riboside (NR)
Nicotinamide riboside (NR) is a form of vitamin B3 that serves as a precursor to NAD+ (nicotinamide adenine dinucleotide), an essential molecule found in every living cell that supports cellular energy production and metabolism. Clinical studies show NR supplementation can effectively increase blood NAD+ levels, though benefits may be most apparent in clinical populations with specific health conditions rather than healthy individuals. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more
Compounds
NMN (Nicotinamide Mononucleotide)
NMN is a naturally occurring compound that serves as a precursor to NAD+, a crucial molecule for cellular energy production and DNA repair. Research suggests it may support healthy aging by improving muscle function, insulin sensitivity, and cardiovascular health. While promising, human clinical trials are still limited and more research is needed to confirm long-term benefits.
Recommended by 3 experts
Learn more
Fatty Acids
Omega-3 Fish Oil (EPA/DHA)
Omega-3 fish oil supplements provide essential fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) that support cardiovascular health, reduce inflammation, and may benefit cognitive function. These supplements are derived from fatty fish and provide concentrated amounts of omega-3s that may be difficult to obtain from diet alone. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 6 experts
Learn more
Compounds
Resveratrol
Resveratrol is a polyphenolic compound naturally found in red wine, grapes, and berries that acts as a powerful antioxidant in the body. Research suggests it may support cardiovascular health, cognitive function, and healthy aging through its anti-inflammatory properties. Clinical studies have shown potential benefits for blood sugar control, weight management, and brain health, though more long-term research is needed.
Recommended by 2 experts
Learn more
Compounds
Spermidine
Spermidine is a naturally occurring polyamine compound that plays a crucial role in cellular autophagy, the body's process of cleaning out damaged cells and regenerating healthier ones. As spermidine levels decline with age, supplementation may support longevity and cognitive function, though long-term human studies are still limited. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more
Vitamins
Vitamin B12 (Cyanocobalamin/Methylcobalamin)
Vitamin B12 is an essential water-soluble vitamin that maintains healthy nerve cells, supports red blood cell formation, and aids in DNA synthesis. It plays a crucial role in brain function, energy metabolism, and preventing megaloblastic anemia. This vitamin is particularly important for neurological health and cognitive function as we age.
Recommended by 5 experts
Learn more
Vitamins
Vitamin D3 (Cholecalciferol)
Vitamin D3 is the active form of vitamin D that supports bone health, immune function, and cardiovascular health by helping the body absorb calcium and phosphorus. Adults over 50 often have reduced vitamin D synthesis and may benefit from supplementation to maintain optimal blood levels. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 6 experts
Learn more
Minerals
Zinc
Zinc is an essential mineral that plays crucial roles in immune function, wound healing, protein synthesis, and DNA formation. It supports over 300 enzymatic reactions in the body and may help reduce the duration of common cold symptoms when taken early. Dietary supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any supplement.
Recommended by 2 experts
Learn more

Choosing Quality Supplements

Third-Party Testing

Look for products tested by NSF, USP, or ConsumerLab for purity and potency verification.

GMP Certified

Good Manufacturing Practices certification ensures consistent quality and safety standards.

Transparent Labels

Avoid proprietary blends. Choose products that list exact amounts of each ingredient.

Bioavailable Forms

Some supplement forms are better absorbed than others. Research the optimal form for each nutrient.

Important Safety Information

This is not medical advice. The supplement information provided here is for educational purposes only. Always consult with a qualified healthcare provider before starting any supplement regimen.

Supplements can interact with medications, have contraindications for certain health conditions, and may not be appropriate for pregnant or nursing women. Quality and dosing can vary significantly between manufacturers.

The presence of a supplement on this page does not constitute an endorsement. We encourage you to research thoroughly and discuss with your healthcare team.