Andrew Huberman's Caffeine Optimization Protocol
Sleep & CircadianA science-based approach to timing and dosing caffeine to optimize mental performance while preserving sleep quality.

PhD, Stanford Neuroscientist
Andrew Huberman, PhD, is a neuroscientist and tenured Professor in the Department of Neurobiology at Stanford University School of Medicine. He has made significant contributions to the fields of brain development, brain plasticity, and neural regeneration. He is the host of the Huberman Lab Podcast, which covers neuroscience and science-based tools for everyday life.
A science-based approach to timing and dosing caffeine to optimize mental performance while preserving sleep quality.
A science-backed cold exposure protocol designed to promote longevity through deliberate cold stress that boosts circulation, reduces inflammation, and enhances cellular repair mechanisms.
Using early morning light exposure to optimize circadian rhythm and improve sleep quality.
Using yoga nidra and similar practices to restore mental and physical energy without sleep.
Prefers single-ingredient supplements for precise dosing
Takes 100-300mg before bed for sleep
Takes 50mg before bed for sleep
Lists as one of three most essential supplements
Takes 5g daily for performance
Takes 140mg-2g before bed for sleep
Takes 5,000-10,000 IU daily
Takes 2-3g daily
Takes 15mg daily via multivitamin for testosterone
Takes 400mg, cycled for testosterone support
Takes 500mg daily
Takes daily for 12+ years as nutritional insurance policy
Takes 1-2g daily for energy and longevity