Supplement Catalog

Explore supplements commonly mentioned in longevity protocols. Each entry includes typical dosing, timing, and important interaction warnings.

NMN (Nicotinamide Mononucleotide)
NMN is a naturally occurring compound that serves as a precursor to NAD+, a crucial molecule for cellular energy production and DNA repair. Research suggests it may support healthy aging by improving muscle function, insulin sensitivity, and cardiovascular health. While promising, human clinical trials are still limited and more research is needed to confirm long-term benefits.
Typical Dosage
250-500mg daily (based on clinical studies showing safety up to 500mg single dose)
When to Take
Take with food, preferably with fatty foods if combining with other supplements like resveratrol
Why for 50+
As we age, our natural NAD+ levels decline significantly, which can impact cellular energy production and DNA repair mechanisms. Adults over 50 may particularly benefit from NMN supplementation as clinical studies have shown improvements in muscle strength, walking distance, and insulin sensitivity in middle-aged and older adults. The age-related decline in NAD+ makes supplementation potentially more beneficial for this population than younger individuals.
Recommended by
AH
Andrew Huberman
Potential Interactions
Blood pressure medications (may enhance hypotensive effects)
Diabetes medications (may affect blood sugar levels due to insulin sensitivity improvements)
Anticoagulants and blood thinners (theoretical interaction due to cardiovascular effects)
Cholesterol-lowering medications (may interact with lipid metabolism pathways)
Generally well-tolerated with minimal documented interactions in current studies

NMN (Nicotinamide Mononucleotide)
NMN is a naturally occurring compound that serves as a precursor to NAD+, a crucial molecule for cellular energy production and DNA repair. Research suggests it may support healthy aging by improving muscle function, insulin sensitivity, and cardiovascular health. While promising, human clinical trials are still limited and more research is needed to confirm long-term benefits.
Typical Dosage
250-500mg daily (based on clinical studies showing safety up to 500mg single dose)
When to Take
Take with food, preferably with fatty foods if combining with other supplements like resveratrol
Why for 50+
As we age, our natural NAD+ levels decline significantly, which can impact cellular energy production and DNA repair mechanisms. Adults over 50 may particularly benefit from NMN supplementation as clinical studies have shown improvements in muscle strength, walking distance, and insulin sensitivity in middle-aged and older adults. The age-related decline in NAD+ makes supplementation potentially more beneficial for this population than younger individuals.
Recommended by
AH
Andrew Huberman
Potential Interactions
Blood pressure medications (may enhance hypotensive effects)
Diabetes medications (may affect blood sugar levels due to insulin sensitivity improvements)
Anticoagulants and blood thinners (theoretical interaction due to cardiovascular effects)
Cholesterol-lowering medications (may interact with lipid metabolism pathways)
Generally well-tolerated with minimal documented interactions in current studies

Choosing Quality Supplements

Third-Party Testing

Look for products tested by NSF, USP, or ConsumerLab for purity and potency verification.

GMP Certified

Good Manufacturing Practices certification ensures consistent quality and safety standards.

Transparent Labels

Avoid proprietary blends. Choose products that list exact amounts of each ingredient.

Bioavailable Forms

Some supplement forms are better absorbed than others. Research the optimal form for each nutrient.

Important Safety Information

This is not medical advice. The supplement information provided here is for educational purposes only. Always consult with a qualified healthcare provider before starting any supplement regimen.

Supplements can interact with medications, have contraindications for certain health conditions, and may not be appropriate for pregnant or nursing women. Quality and dosing can vary significantly between manufacturers.

The presence of a supplement on this page does not constitute an endorsement. We encourage you to research thoroughly and discuss with your healthcare team.