Supplement Catalog

Explore supplements commonly mentioned in longevity protocols. Each entry includes typical dosing, timing, and important interaction warnings.

1 supplement found

Vitamin B12 (Cyanocobalamin/Methylcobalamin)
Vitamin B12 is an essential water-soluble vitamin that maintains healthy nerve cells, supports red blood cell formation, and aids in DNA synthesis. It plays a crucial role in brain function, energy metabolism, and preventing megaloblastic anemia. This vitamin is particularly important for neurological health and cognitive function as we age.
Typical Dosage
2.4 mcg daily (RDA) for maintenance; 500-1000 mcg daily for correcting deficiency; up to 2000 mcg for seniors with absorption issues
When to Take
Can be taken with or without food; morning preferred to avoid potential sleep interference; sublingual forms may be held under tongue for 30 seconds
Why for 50+
Adults over 50 have significantly reduced stomach acid production, which impairs the body's ability to extract B12 from food sources. Additionally, the prevalence of B12 deficiency increases dramatically with age, affecting 10-15% of adults over 60. Many seniors take medications like proton pump inhibitors or metformin that further reduce B12 absorption, making supplementation particularly important for maintaining cognitive function and preventing neuropathy.
Recommended by
JF
Joel Fuhrman
Potential Interactions
Metformin (diabetes medication) - can reduce B12 absorption with long-term use
Proton pump inhibitors (omeprazole, lansoprazole) - reduce stomach acid needed for B12 absorption
H2 receptor antagonists (ranitidine, famotidine) - may decrease B12 absorption
Colchicine (gout medication) - can impair B12 absorption
Chloramphenicol (antibiotic) - may reduce effectiveness of B12 supplementation

Vitamin B12 (Cyanocobalamin/Methylcobalamin)
Vitamin B12 is an essential water-soluble vitamin that maintains healthy nerve cells, supports red blood cell formation, and aids in DNA synthesis. It plays a crucial role in brain function, energy metabolism, and preventing megaloblastic anemia. This vitamin is particularly important for neurological health and cognitive function as we age.
Typical Dosage
2.4 mcg daily (RDA) for maintenance; 500-1000 mcg daily for correcting deficiency; up to 2000 mcg for seniors with absorption issues
When to Take
Can be taken with or without food; morning preferred to avoid potential sleep interference; sublingual forms may be held under tongue for 30 seconds
Why for 50+
Adults over 50 have significantly reduced stomach acid production, which impairs the body's ability to extract B12 from food sources. Additionally, the prevalence of B12 deficiency increases dramatically with age, affecting 10-15% of adults over 60. Many seniors take medications like proton pump inhibitors or metformin that further reduce B12 absorption, making supplementation particularly important for maintaining cognitive function and preventing neuropathy.
Recommended by
JF
Joel Fuhrman
Potential Interactions
Metformin (diabetes medication) - can reduce B12 absorption with long-term use
Proton pump inhibitors (omeprazole, lansoprazole) - reduce stomach acid needed for B12 absorption
H2 receptor antagonists (ranitidine, famotidine) - may decrease B12 absorption
Colchicine (gout medication) - can impair B12 absorption
Chloramphenicol (antibiotic) - may reduce effectiveness of B12 supplementation

Choosing Quality Supplements

Third-Party Testing

Look for products tested by NSF, USP, or ConsumerLab for purity and potency verification.

GMP Certified

Good Manufacturing Practices certification ensures consistent quality and safety standards.

Transparent Labels

Avoid proprietary blends. Choose products that list exact amounts of each ingredient.

Bioavailable Forms

Some supplement forms are better absorbed than others. Research the optimal form for each nutrient.

Important Safety Information

This is not medical advice. The supplement information provided here is for educational purposes only. Always consult with a qualified healthcare provider before starting any supplement regimen.

Supplements can interact with medications, have contraindications for certain health conditions, and may not be appropriate for pregnant or nursing women. Quality and dosing can vary significantly between manufacturers.

The presence of a supplement on this page does not constitute an endorsement. We encourage you to research thoroughly and discuss with your healthcare team.